List of Scientific Papers Supplied to SEAC Members by the Secretariat

29th November - 28th February 2001


Paper by K Holada and J Vostal, 'Different levels of prion protein (PrPc) expression on hamster, mouse and human blood levels', published in the British Journal of Haematology, 2000, volume 110, pages 472-480;

Paper by C Korth, K Kaneko and S Prusiner, 'Expression of unglycosylated mutated prion protein facilitates PrPSc formation in neuroblastoma cells infected with different prion strains', published in the Journal of General Virology, 2000, volume 81, pages 2555-2563;

Paper by M Bruce, K Brown, N Mabbott, C Farquhar and M Jeffrey, 'Follicular dendritic cells in TSE pathogenesis', published in Immunology Today, 2000, volume 21, pages 442-446;

Paper by A McLean and C Bostock, 'Scrapie infections initiated at varying doses: an analysis of 117 titration experiments', published in The Royal Society, 2000, volume 355, pages 1043-1050;

Paper by M Stevenson, J Wilesmith, J Ryan, R Morris, J Lockhart, D Lin and R Jackson, 'Temporal aspects of the epidemic of bovine spongiform encephalopathy in Great Britain: individual animal-associated risk factors for the disease', published in the Veterinary Record, 2000, volume 147, pages 349-354;

Paper by J Wilesmith, J Ryan, M Stevenson, R Morris, D Pfeiffer, D Lin, R Jackson and R Sanson, 'Temporal aspects of the epidemic of bovine spongiform encephalopathy in Great Britain: holding-associated risk factors for the disease', published in the Veterinary Record, 2000, volume 147, pages 319-325;

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Paper by S Mouillet-Richard, M Ermonval, C Chebassier, J Laplanche, S Lehmann, J Launay and O Kellerman, 'Signal transduction through prion protein', published in Science, 2000, volume 289, pages 1925-1928;

Paper by P Parchi, W Zou, W Wang, P Brown, S Capellari, B Ghetti, N Kopp, W Schulz-Schaeffer, H Kretzschmar, M Head, J Ironside, P Gambetti and S Chen, 'Genetic influence on the structural variations of the abnormal prion protein', published in PNAS, 2000, volume 97, pages 10168-10172;

Paper by G Kovacs, M Head, T Bunn, L Laszlo, R Will and J Ironside, 'Clinicopathological phenotype of codon 129 valine homozygote sporadic Creutzfeldt-Jakob disease', published in Neuropathology and Applied Neurobiology, 2000, volume 26, pages 463-472;

Paper by C Verity, A Nicoll, R Will, G Devereux and L Stellitano, 'Variant Creutzfeldt-Jacob disease in UK children: a national surveillance study', published in the Lancet, 2000, volume 356, pages 1224-27;

Article by Haroon Ashraf, 'The first case of mother-to-child transmission of vCJD?', published in the Lancet, 2000, volume 356, page 1085;

Paper by K Doh-Ura, E Mekada, K Ogomori and T Iwaki, 'Enhanced CD9 expression in the mouse and human brains infected with transmissible spongiform encephalopathies', published in the Journal of Neuropathology and Experimental Neurology, 2000, volume 59, pages 774-785;

Paper by V Iniguez, D McKenzie, J Mirwald and J Aiken, 'Strain-specific propagation of PrPSc properties into baculovirus-expressed hamster PrPC', published in the Journal of General Virology, 2000, volume 81, pages 2565-2571;

Paper by K O'Rourke, T Baszler, T Besser, J Miller, R Cutlip, G Wells, S Ryder, S Parish, A Hamir, N Cockett, A Kenny and D Knowles, 'Preclinical diagnosis of scrapie by immunohistochemistry of third eyelid lymphoid tissue', published in the Journal of Clinical Microbiology, 2000, volume 38, pages 3254-3259;

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Letter to the editor by M Feughelman and B Willis, 'Thiol-disulfide interchange a potential key to conformational change associated with amyloid fibril formation', published in the Journal of Theoretical Biology, 2000, volume 206, pages 313-315;

Paper by J Herms, S Korte, S Gall, I Schneider, S Dunker and H Kretzschmar, 'Altered intracellular calcium homeostasis in cerebellar granule cells of prion protein-deficient mice', published in the Journal of Neurochemistry, 2000, volume 75, pages 1487-1492;

Paper by A Aguzzi and F Heppner, 'Pathogenesis of prion diseases: a progress report', published in Cell Death and Differentiation, 2000, volume 7, pages 889-902;

Paper by F Hafiz and D Brown, 'A model for the mechanism of astrogliosis in prion disease', published in Molecular and Cellular Neuroscience, 2000, volume 16, pages 221-232;

Paper by Y Hirakura, W Yiu, A Yamamoto and B Kagan, 'Amyloid peptide channels: blockade by zinc and inhibition by Congo red (amyloid channel block)', published in Amyloid, 2000, volume 7, pages 194-199;

Paper by A Thompson, A White, C McLean, C Masters, R Cappai and C Barrow, 'Amyloidogenicity and neurotoxicity of peptides corresponding to the helical regions of PrPC', published in the Journal of Neuroscience Research, 2000, volume 62, pages 293-301;

Paper by L Manueldis and Z Yun Lu, 'Attenuated Creutzfeldt-Jacob disease agents can hide more virulent infections', published in Neuroscience Letters, 2000, volume 293, pages 163-166;

Paper by G Raymond, A Bossers, L Raymond, K O'Rourke, L McHolland, P Bryant III, M Miller, E Williams, M Smits and B Caughey, 'Evidence of a molecular barrier limiting susceptibility of humans, cattle and sheep to chronic wasting disease', published in the EMBO Journal, 2000, volume 19, pages 4425-4430;

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Letter to the editor by D Taylor, K Fernie, H Reichl and R Somerville, 'Infectivity in the blood of mice with a BSE-derived agent', published in the Journal of Hospital Infection, 2000, volume 46, pages 78-79;

Letter to the editor by A Shmakov, N McLennan, P McBride, C Farquhar, J Bode, K Rennison and S Ghosh, 'Cellular prion protein is expressed in the human enteric nervous system', published in Nature Medicine, 2000, volume 6, pages 840-841;
Feature by Dorothy Boon, 'Future uncertain for reliable vCLD screening tests', published in the Lancet, 2000, volume 356, page 228;

Article by John Griffin, 'Epidemiology of bovine spongiform encephalopathy in Ireland', published in the Irish Veterinary Journal, 2000, volume 53, pages 529-532;

Paper by M Glatzel and A Aguzzi, 'PrPC expression in the peripheral nervous system is a determinant of prion neuroinvasion', published in the Journal of General Virology, 2000, volume 81, pages 2813-2821;

Paper by M Stevenson, J Wilesmith, J Ryan, A Lawson, D Pfeiffer and D Lin, 'Descriptive spatial analysis of the epidemic of bovine spongiform encephalopathy in Great Britain to June 1997', published in the Veterinary Record, 2000, volume 147, pages 379-384;

Paper by I Begara-McGorum, A Clark, S Martin and M Jeffrey, 'Prevalence of vacuolar lesions consistent with scrapie in the brains of healthy cull sheep of the Shetland Islands', published in the Veterinary Record, 2000, volume 147, pages 439-441;

Paper by J Moorby, M Dhanoa and A Austin, 'Aspects of the incubation of dairy cows during the incubation of bovine spongiform encephalopathy', published in the Veterinary Record, 2000, volume 147, pages 409-412;

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Paper by M Baylis, F Houston, W Goldmann, N Hunter and A McLean, 'The signature of scrapie: differences in the PrP genotype profile of scrapie-affected and scrapie-free UK sheep flocks', published in The Royal Society, 2000, volume 267, pages 2029-2035;

Letter to the editor by D Taylor, K Fernie, H Reichl and R Somerville, 'Infectivity in the blood of mice with a BSE-derived agent', published in the Journal of Hospital Infection, 2000, volume 46, pages 78-79;

Paper by M Prevost, F Jacquemotte, K Oberg, D Staelens, B Devreese and J Van Beeumen, 'Conformational variability of the synthetic peptide 129-141 of the mouse prion protein', published in the Journal of Biomolecular Structure and Dynamics, 2000, volume 18, pages 237-248;

Abstract by A Green, E Thompson, M Zeidler, G Stewart, J Mackenzie, M Macleod, R Knight and R Will, 'Raised concentrations of brain specific proteins in patients with sporadic and variant CJD', published in the Journal of Neurology, Neurosurgery and Psychiatry, 2000, volume 69, page 419;

Paper by J Kourie and A Culverson, 'Prion peptide fragment PrP[106-126] forms distinct cation channel types', published in the Journal of Neuroscience Research, 2000, volume 62, pages 120-133;

Paper by Jeffery Kelly, 'Mechanisms of amyloidogenesis', published in Nature structural biology, 2000, volume 7, number 10, pages 824-826;

Paper by G Keshet, O Bar-Peled, D Yaffe, U Nudel and R Gabizon, 'The cellular prion protein colocalizes with the dystroglycan complex in the brain', published in the Journal of Neurochemistry, 2000, volume 75, pages 1889-1897;

Paper by B Wong, C Venien-Bryan, R Williamson, D Burton, P Gambetti, M-Sun Sy, D Brown and I Jones, 'Copper refolding of prion protein', published in Biochemical and Biophysical Research Communications, 2000, volume 276, pages 1217-1224;

Paper by M Klein and A Aguzzi, 'The neuroimmune interface in prion diseases', published in News in Physiological Sciences, 2000, volume 15, pages 250-255;

Paper by A Li, S Sakaguchi, K Shigematsu, R Atarashi, B Roy, R Nakaoke, K Arima, N Okimura, J Kopacek and S Katamine, 'Physiological expression of the gene for PrP-like protein, PrPLP/Dpl, by brain endothelial cells and its ectopic expression in neurons of PrP-deficient mice ataxic due to purkinje cell degeneration', published in the American Journal of Pathology, 2000, volume 157, pages 1447-1452;

Paper by D Stephenson, K Chiotti, C Ebeling, D Groth, S DeArmond, S Prusiner and G Carlson, 'Quantitative trait loci affecting prion incubation time in mice', published in Genomics, 2000, volume 69, pages 47-53;

Paper by M Miller, E Williams, C McCarty, T Spraker, T Kreeger, C Larsen and E Thorne, 'Epizootiology of chronic wasting disease in free-ranging cervids in Colorado and Wyoming', published in the Journal of Wildlife Diseases, 2000, volume 36, pages 676-690;

Paper by M Conner, C McCarty and M Miller, 'Detection of bias in harvest-based estimates of chronic wasting disease prevalence in mule deer', published in the Journal of Wildlife Diseases, 2000, volume 36, pages 691-699;

Paper by C Riemer, I Queck, D Simon, R Kurth and M Baier, 'Identification of upregulated genes in scrapie-infected brain tissue', published in the Journal of Virology, 2000, volume 74, pages 10245-10248;

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