List of Scientific Papers Supplied to SEAC Members by the Secretariat

16th February - 11th May 2000


Paper by C von Holst, K Honikel, W Unglaub, G Kramer and E Anklam, 'Determination of an appropriate heat treatment of animal waste using the ELISA technique: results of a validation study', published in Meat Science, 2000, volume 54, number 1, pages 1-7;

Paper by R Race, M Oldstone and B Chesebro, 'Entry versus blockade of brain infection following oral or intraperitoneal scrapie administration: Role of prion protein expression in peripheral nerves and spleen', published in Journal of Virology, 2000, volume 74, number 2, pages 828-833;

Abstract by D Brown, B Wong and I Jones, 'Recombinat prion protein exhibits superoxide dismutase activity', published in Journal of Neurochemistry, 1999, volume 73, supplement 19;

Abstract by T Appel, D Kirsch, R Kaufmann and D Reisner, 'Prion rods contain small amounts of two host sphingolipids as revealed by high performance thin layer chromatography and maldi mass spectrometry', published in Journal of Neurochemistry, 1999, volume 73, supplement 159;

Paper by G Puoti, G Giaccone, G Rossi, B Canciani, O Bugiani and F Tagliavini, 'Sporadic creutzfeldt-jacob disease: Co-occurrence of different types of PrPsc in the same brain', published in Neurology, 1999, volume 53, number 9, pages 2173-2176;

Paper by David Brown, 'Prion protein expression aids cellular uptake and veratridine-induced release of copper', published in Journal of Neuroscience Research, 1999, volume 58, number 5, pages 717-725;

Paper by P Brown, L Cervenakova, L McShane, P Barber, R Rubenstein and W Drohan, 'Further studies of blood infectivity in an experimental model of transmissible spongiform encephalopathy, with an explanation of why blood components do not transmit Creutzfeldt-Jacob disease in humans', published in Transfusion, 1999, volume 39, number 11-12, pages 1169-1178;

Paper by J-Il Kim, W-Kyu Ju, J-Ho-Choi, J Kim, E-Kyoung Choi, R Carp, H Wisniewski and Y-Sun Kim, 'Expression of cytokine genes and increased nuclear factor-kappa B activity in the brains of scrapie-infected mice', published in Molecular Brain Research, 1999, volume 73, N1-2, pages 17-27;

Paper by K Rodolfo, R Hassig, K Moya, Y Frobert, J Grassi and L Di Giamberardino, 'A novel cellular prion protein isoform present in rapid anterograde axonal transport', published in Neuroreport, 1999, volume 10, number 17, pages 3639-3644;

Paper by A McKie, P Zammit and R Naftalin, 'Comparison of cattle and sheep colonic permeabilities to horseradish peroxidase and hamster scrapie prion protein in vitro', published in Gut, 1999, volume 45, number 6, pages 879-888;

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Paper by S Supattapone, H Nguyen, F Cohen, S Prusiner and M Scott, 'Elimination of prions by branched polyamines and implications for therapeutics', published in PNAS, 1999, volume 96, number 25, pages 14529-34;
Paper by C Weissmann and A Aguzzi, 'PrP's Double causes trouble', published in Science, 1999, volume 286, pages 914-915;

Paper by J Pammer, A Suchy, M Rendl and E Tschachler, 'Cellular prion protein expressed by bovine squamous epithelia of skin and upper gastrointestinal tract', published in the Lancet, 1999, volume 354, pages 1702-3;

Paper by J Kopacek, S Sakaguchi, K Shigematsu, N Nishida, R Atarashi, R Nakaoke, R Moriuchi, M Niwa and S Katamine, 'Upregulation of the genes encoding lysosomal hydrolases, a perforin-like protein, and peroxidases in the brains of mice affected with an experimental prion disease', published in Journal of Virology, 2000, volume 74, number 1, pages 411-417;

Paper by N Nishida, D Harris, D Vilette, H Laude, Y Frobert, J Grassi, D Casanova, O Milhavet and S Lehmann, 'Successful transmission of three mouse-adapted scrapie strains to murine neuroblastoma cell lines overexpressing wild-type mouse prion protein', published in Journal of Virology, 2000, volume 74, number 1, pages 320-325;

Paper by M Beekes and P McBride, 'Early accumulation of pathological PrP in the enteric nervous system and gut-associated lymphoid tissue of hamsters orally infected with scrapie', published in Neuroscience Letters, 2000, volume 278, pages 181-184;

Paper by G Barclay, J Hope, C Birkett and M Turner, 'Distribution of cell-associated prion protein in normal adult blood determined by flow cytometry', published in the British Journal of Haematology, 1999, volume 107, number 4, pages 804-814;

Paper by D Brown, B Wong, F Haziz, C Clive, S Haswell and I Jones, 'Normal prion protein has an activity like that of superoxide dismutase', published in the Biochemical Journal, 1999, volume 344, pages 1-5;

Paper by T Appel, C Dumpitak, U Matthiesen and D Riesner, 'Prion rods contain an inert Polysaccharide Scaffold', published in Biological Chemistry, 1999, volume 380, pages 1295-1306;

Review by C L Masters, 'Story of an obsession', published in Nature, 1999, volume 402, pages 581-582;

Paper by A Raeber and A Aguzzi, 'Engulfment of prions in the germinal centre', published in Immunology Today, 2000, volume 21, number 2, pages 66-67;
Paper by A Bossers, R de Vries and M Smits, 'Susceptibility of sheep for scrapie as assessed by in vitro conversion of nine naturally occurring variants of PrP', published in the Journal of Virology, 2000, volume 74, number 3, pages 1407-1414;

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Paper by C Soto, R Kascsak, G Saborio, P Aucouturier, T Wisniewski, F Prelli, R Kascsak, E Mendez, D Harris, J Ironside, F Tagliavini, R Carp and B Frangione, 'Reversion of prion protein conformational changes by synthetic (-sheet breaker peptides', published in the Lancet, 2000, volume 355, pages 192-197;

Review by Graham Medley, 'Integrals of disease', published in Nature, 2000, volume 403, page 138;

Paper by James Hope, 'Breech-birth prions', published in Nature, 1999, volume 402, page 737;

Paper by L Li and S Lindquist, 'Creating a protein-based element of inheritance', published in Science, 2000, volume 287, pages 661-664;

Paper by M Head and J Ironside, 'Inhibition of prion-protein conversion: a therapeutic tool?', published in Trends in Microbiology, 2000, volume 8, number 1, pages 6-8;

Paper by J Madec, P Belli, D Calavas and T Baron, 'Efficiency of Western blotting for the specific immunodetection of proteinase K-resistant prion protein in BSE diagnosis in France', published in the Veterinary Record, 2000, volume 146, pages 74-76;

Paper by M Hardt, T Baron and M Groschup, 'A comparative study of immunohistochemical methods for detecting abnormal prion protein with monoclonal and polyclonal antibodies', published in the Journal of Comparative Pathology, 2000, volume 122, pages 43-53;

Paper by K Adjou, N Privat, S Demart, J Deslys, M Seman, J Hauw and D Dormont, 'MS-8209, an amphotericin B analogue, delays the appearance of spongiosis, astrogliosis and PrPres accumulation in the brain of scrapie-infected hamsters', published in the Journal of Comparative Pathology, 2000, volume 122, pages 3-8;

Paper by W Schulz-Schaeffer, S Tschoke, N Kranefuss, W Drose, D Hause-Reitner, A Giese, M Groschup and H Kretzschmar, 'The paraffin-embedded tissue blot detects PrPsc early in the incubation time in prion diseases', published in the American Journal of Pathology, 2000, volume 156, number 1, pages 51-56;
Paper by Z Kanyo, K Pan, R Williamson, D Burton, S Prusiner, R Fletterick and F Cohen, 'Antibody binding defines a structure for an epitope that participates in the PrPc (PrPSc conformational change', published in Journal of Molecular Biology, 1999, volume 293, number 4, pages 855-863;

Paper by Adriano Aguzzi, 'Prion diseases, blood and the immune system: concerns and reality', published in Haematologica, 2000, volume 85, number 1, pages 3-10;
Correspondence by Heino Diringer, 'Contaminated surgical instruments and variant Creutzfeldt-Jacob disease', published in the Lancet, 1999, volume 354, pages 1823-1824;

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Paper by N Shiraishi, Y Ohta and M Nishikimi, 'The octapeptide repeat region of prion protein binds Cu(II) in the redox-inactive state', published in Biochemical and Biophysical Research Communications, 2000, volume 267, number 1, pages 398-402;

Paper by David Brown, 'Prion protein peptides: Optimal toxicity and peptide blockade of toxicity', published in Molecular and Cellular Neuroscience, 2000, volume 15, pages 66-78;

Abstract by M Sugaya, K Nakamura, T Watanabe, N Yasaka, Y Koyama, S Irie, T Yokoyama, S Itohara and K Tamaki, 'Murine langerhans cells and keratinocytes express cellular prion-related protein: Possible mechanism of development of Spongiform Encephalopathy through the skin', published in the Journal of Investigative Dermatology, 2000, volume 114, page 218;

Paper by A Ghani, C Donnelly, N Ferguson and R Anderson, 'Assessment of the prevalence of vCJD through testing tonsils and appendices for abnormal prion protein', published in Proceedings of the Royal Society of London Series B Biological Sciences, 2000, volume 267, pages 23-29;

Paper by A McLean, A Hoek, L Hoinville and M Gravenor, 'Scrapie transmission in Britain: a recipe for a mathematical model', published in Proceedings of the Royal Society of London Series B Biological Sciences, 1999, volume 266, pages 2531-2538.

Paper by A Aguzzi, M Klein, C Musahl, A Raeber, T Blattler, I Hegyi, R Frigg and S Brandner, 'Use of brain grafts to study the pathogenesis of prion diseases', published in Essays in Biochemistry, 1998, volume 33, pages 133-147;
Paper by S Capellari, S Zaidi, C Urig, G Perry, M Smith and R Petersen, 'Prion protein glycosylation is sensitive to redox change', published in The Journal of Biological Chemistry, 1999, volume 274, number 49, pages 34846-34850;

Abstract by K Holada, J Vostal, P Theisen, C MacAuley and R Rohwer, 'Scrapie infectivity in hamster blood cells does not concentrate in platelets but is enriched in peripheral leukocytes', published in Blood, 1999, volume 94, number 10, page 1091;

Review by S Dawson, 'The risk of infection by blood transfusion in England', published in the Journal of Clinical Pathology, 2000, volume 53, number 1, page 85;

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Paper by A E Wrathall, 'Risks of transmission of spongiform encephalopathies by reproductive technologies in domesticated ruminants', published in Livestock Production Science, 2000, volume 62, number 3, pages 287-316;

Paper by D M Asher, 'The transmissible spongiform encephalopathy agents: concerns and responses of United States regulatory agencies in maintaining the safety of biologics', published in Developments in Biological Standardization, 1999, volume 100, pages 103-118;

Paper by D Vilette, M Madelaine and H Laude, 'Establishment of astrocyte cell lines from sheep genetically susceptible to scrapie', published in In Vitro Cellular & Development Biology-Animal, 2000, volume 36, pages 45-49;

Paper by K Kimura, M Kubo and T Yokoyama, 'Characteristics of prion protein in the brains of hamsters inoculated serially with a mouse-passaged scrapie strain', published in the Journal of Comparative Pathology, 2000, volume 122, pages 123-130;

Paper by S Ryder, S Hawkins, M Dawson and G Wells, 'The neuropathology of experimental bovine spongiform encephalopathy in the pig', published in the Journal of Comparative Pathology, 2000, volume 122, pages 131-143;

Paper by S Priola, A Raines and W Caughey, 'Porphyrin and Phthalocyanine and antiscrapie compounds', published in Science, 2000, volume 287, number 5457, pages 1503-1506;

Paper by M Jeffrey, W Halliday, J Bell, A Johnston, N Macleod, C Ingham, A Sayers, D Brown and J Fraser, 'Synapse loss associated with abnormal PrP precedes neuronal degeneration in the scrapie-infected murine hippocampus', published in Neuropathology and Applied Neurobiology, 2000, volume 26, number 1, pages 41-54;

Paper by E Graner, A Mercadante, S Zanata, O Forlenza, A Cabral, S Veiga, M Juliano, R Roesler, R Walz, A Minetti, I Izquierdo, V Martins and R Brentani, 'Cellular prion protein binds laminin and mediates neuritogenesis', published in Molecular Brain Research, 2000, volume 76, pages 85-92;

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Paper by F Dandy-Dron, L Benboudjema, F Guillo, A Jaegly, C Jasmin, D Dormont, M Tovey and M Dron, 'Enhanced levels of scrapie responsive gene mRNA in BSE-infected mouse brain', published in Molecular Brain Research, 2000, volume 76, pages 173-179;

Paper by T Hagenaars, N Ferguson, C Donnelly, A Ghani and R Anderson, 'Feed-borne transmission and case clustering of BSE', published in Proceedings of the Royal Society of London Series B Biological Sciences, 2000, volume 267, pages 205-215.

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